Reattachment of amputated parts of the body (Replantation) has become a reality since the first arm replant was carried out six decades ago.Failures were not uncommon in the beginning, leading on to the analysis of the problem and refinements in technique.Improvements in sutures, instrumentation and better microscopes further helped the surgeons to
Spectrum of vitriolage in India: A retrospective data record-based study
Introduction: Vitriolage or acid attack or acid throwing is a gender-based terrible violent crime.There are many everlasting sequels of vitriolage which consist of permanent scarring of the face or body, blindness as well as socioeconomic and psychological intricacy.The sufferer of acid attack is competitor, hatred, enmity or jealousy.Vitriolage ar
Parvalbumin interneurons provide spillover to newborn and mature dentate granule cells
Parvalbumin-expressing interneurons (PVs) in the dentate gyrus provide activity-dependent regulation of adult neurogenesis as well as maintain inhibitory control of mature neurons.In mature neurons, PVs evoke GABAA postsynaptic currents (GPSCs) with fast rise and decay phases that allow precise control of Earrings spike timing, yet synaptic current
Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage
Abstract Aneuploidy is a hallmark of human cancer, yet the molecular Gift Card mechanisms to cope with aneuploidy-induced cellular stresses remain largely unknown.Here, we induce chromosome mis-segregation in non-transformed RPE1-hTERT cells and derive multiple stable clones with various degrees of aneuploidy.We perform a systematic genomic, transc
Autologous stem-cell transplantation as consolidation of first-line chemotherapy in patients with peripheral T-cell lymphoma: a multicenter GELTAMO/FIL study
Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of rare lymphoid malignancies Mittens + Scarves that mostly have poor prognoses with currently available treatments.Upfront consolidation with autologous stem cell transplantation (ASCT) is frequently carried out, but its efficacy has never been investigated in randomized trials.We design